PLGA(40k)-PEG(5k)-DBCO is a polymer with both hydrophobic (poly(lactide-co-glycolide)/PLGA) and hydrophilic (PEG) blocks. The self-assembly of the polymer in water occurs with PLGA being shielded at the core by PEG shell. The hydrophobic core can be used to encapsulate lipophilic drugs while the PEG shell offers protection against (enzymatic/hydrolysis) degradation in drug delivery/nanomedicine. The DBCO is reactive with azide via copper-free click chemistry to form a stable triazole bond. Reagent grade, for research purpose.
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