Azide-PEG8-Amido-tri-(carboxyethoxymethyl)-methane is a multifunctional reagent combining an azide group and three carboxylic acids. The azide group is reactive towards terminal alkynes or strained cyclooctynes such as DBCO and BCN. The carboxylic acids can react with primary amines or other nucleophiles to form stable amide bonds. Finally, the PEG spacer and amide bonds provide aqueous solubility to this molecule.
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