HO-PLGA-acid (LA/GA 85:15), MW 40,000 is a block copolymer containing a hydrophobic poly(lactide-co-glycolide) (PLGA) block chemically attached to a hydrophilic PEG block with a carboxylic acid. The ratio of lactide to glycolide is 85:15. The polymer has a terminal carboxyl which can react with amine (NH2) molecule to form a stable amide linkage in presence of activator, such as HATU or EDC. Upon dispersion in water, the polymer self assembles to form micelles which can encapsulate drugs for drug delivery. Reagent grade, for research use only.
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