Amino-SS-PEG12-acid

Amino-SS-PEG12-acid


Amino-SS-PEG12-acid is a cleavable linker molecule. The disulfide bonds can be cleaved by Dithiothreitol (DTT) reagent. The terminal amine can be reacted with carboxylic acid, activated NHS esters and other carbonyl compounds. The terminal carboxylic acid can be reacted with primary amines in the presence of activators such as EDC and HATU to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

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