Antibody

Antibody

Antibodies are also known as immunoglobulins (Ig) which made by a certain type of white blood cell that's called a B cell. They are made up of four chains, two identical light chains and two identical heavy chains, held together by disulfide bonds to form a flexible Y shape.

Antibodies play an important role in research areas such as antibody drug conjugates (ADC) development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.

BroadPharm provides two classes of antibodies:

• Anti-drug antibodies are commonly used for detection and quantification of therapeutic antibodies during the drug development process. These anti-drug antibodies are suitable for ADC in vivo PK, PD studies. They are specifically binding to ADC's drug payloads (MMAE, DM1/DM4...) in ELISA assay.
• Therapeutic Monoclonal Antibody (mAb) is a class of biological drugs that are used to treat a variety of diseases by targeting specific antigens. The current humanized synthetic therapeutic monoclonal antibodies use the body's natural antibodies to trigger a biological response. Each antibody recognizes only one antigen, allowing for precise attacks on specific targets.

Anti-drug antibody
Therapeutic antibody