Products

BCN-PEG3-VC-PFP Ester

Linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The BCN group can react with azide-tagged biomolecules. The PFP ester is a better leaving group compared to a hydroxyl group and can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Catalog #:
BP-24334
Name:
BCN-PEG3-VC-PFP Ester
Formula:
C37H50F5N5O10
MW:
819.8
CAS:
2353409-45-5
Purity:
96%
Availability:
In Stock
Ships within:
24 hours
Storage condition:
-20 ° C
Shipping:
Ambient Temperature
Solubility:
DMSO, DCM, DMF
UNIT
PRICE
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