BCN-PEG3-VC-PFP Ester

BCN-PEG3-VC-PFP Ester


BCN-PEG3-VC-PFP Ester is a cleavable ADC linker featuring a BCN group, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PFP ester. The PFP ester is activated towards nucleophilic attack from amines, while BCN is a click chemistry handle which readily forms stable triazoles with azide groups on a target molecule. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery.

Molecular structure of the compound BP-24334
    • Unit
    • Price
    • Qty
    • 50 MG
    • $480.00
    • 100 MG
    • $840.00
    • 250 MG
    • $1600.00
    • 500 MG
    • $2800.00

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