PROTAC Linkers

PROTAC Linkers


PROTAC linker is a crosslinker that connects two functional motifs of a PROTAC, a target protein binder and an E3 ligase recruiter. Most commonly used PROTAC linkers in the development of PROTACs are PEGs, Alkyl-Chain and Alkyl/ether. Insertion of PEG increases the water-solubility of the molecules.

Catalog Product Name Structure M.W. Purity Pricing
VHL Ligand 1
BP-24441VHL Ligand 1 HCl saltMolecular structure of the compound: VHL Ligand 1 HCl salt430.698%Pricing
(S, R, S)-AHPC-acid
BP-24508(S, R, S)-AHPC-pentanoic-acidMolecular structure of the compound: (S, R, S)-AHPC-pentanoic-acid558.798%Pricing
BP-28095(S, R, S)-AHPC-nanoly-acidMolecular structure of the compound: (S, R, S)-AHPC-nanoly-acid614.8Pricing
(S,R. S)-AHPC-PEG-acid
BP-24450(S, R, S)-AHPC-PEG2-acidMolecular structure of the compound: (S, R, S)-AHPC-PEG2-acid618.898%Pricing
BP-24504(S, R, S)-AHPC-PEG3-acidMolecular structure of the compound: (S, R, S)-AHPC-PEG3-acid662.898%Pricing
BP-24468(S, R, S)-AHPC-PEG4-acidMolecular structure of the compound: (S, R, S)-AHPC-PEG4-acid706.998%Pricing
BP-25701(S, R, S)-AHPC-PEG6-acidMolecular structure of the compound: (S, R, S)-AHPC-PEG6-acid79598%Pricing
BP-24506(S, R, S)-AHPC-PEG8-acidMolecular structure of the compound: (S, R, S)-AHPC-PEG8-acid88398%Pricing
(S,R.S)-AHPC-PEG-NHS ester
BP-25121(S, R, S)-AHPC-PEG2-NHS esterMolecular structure of the compound: (S, R, S)-AHPC-PEG2-NHS ester715.898%Pricing
BP-25120(S, R, S)-AHPC-PEG4-NHS esterMolecular structure of the compound: (S, R, S)-AHPC-PEG4-NHS ester803.998%Pricing
BP-25703(S, R, S)-AHPC-PEG6-NHS esterMolecular structure of the compound: (S, R, S)-AHPC-PEG6-NHS ester892Pricing
BP-23982(S, R, S)-AHPC-PEG8-NHS esterMolecular structure of the compound: (S, R, S)-AHPC-PEG8-NHS ester980.298%Pricing
(S,R. S)-AHPC-PEG-amine
BP-24451(S, R, S)-AHPC-PEG2-amine hydrochloride saltMolecular structure of the compound: (S, R, S)-AHPC-PEG2-amine hydrochloride salt575.798%Pricing
BP-27855(S, R, S)-AHPC-PEG3-amine hydrochloride saltMolecular structure of the compound: (S, R, S)-AHPC-PEG3-amine hydrochloride salt619.8Pricing
BP-24446(S, R, S)-AHPC-PEG4-amine hydrochloride saltMolecular structure of the compound: (S, R, S)-AHPC-PEG4-amine hydrochloride salt663.898%Pricing
(S,R. S)-AHPC-PEG-Azide
BP-24458(S, R, S)-AHPC-PEG4-AzideMolecular structure of the compound: (S, R, S)-AHPC-PEG4-Azide703.998%Pricing
(S,R. S)-AHPC-PEG-tosyl
BP-28053(S, R, S)-AHPC-PEG2-TosMolecular structure of the compound: (S, R, S)-AHPC-PEG2-Tos700.998%Pricing
BP-24474(S, R, S)-AHPC-PEG4-tosylMolecular structure of the compound: (S, R, S)-AHPC-PEG4-tosyl78997%Pricing
BP-28058(S, R, S)-AHPC-PEG6-TosMolecular structure of the compound: (S, R, S)-AHPC-PEG6-Tos877.198%Pricing
EGFR PROTAC
BP-27854SJF 1521Molecular structure of the compound: SJF 15211074.7Pricing
MZ1
BP-27846MZ1Molecular structure of the compound: MZ11002.7Pricing
E3 ligase Ligand 19
BP-24503E3 ligase Ligand 19Molecular structure of the compound: E3 ligase Ligand 19532.6Pricing
Thalidomide
BP-30256ThalidomideMolecular structure of the compound: Thalidomide258.298%Pricing
BP-279643-{5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}piperidine-2,6-dioneMolecular structure of the compound: 3-{5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}piperidine-2,6-dione259.2Pricing
BP-244374-Hydroxy-thalidomideMolecular structure of the compound: 4-Hydroxy-thalidomide274.298%Pricing
BP-279655-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneMolecular structure of the compound: 5-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione273.3Pricing
BP-244304-Fluoro-thalidomideMolecular structure of the compound: 4-Fluoro-thalidomide276.298%Pricing
BP-279662-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dioneMolecular structure of the compound: 2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione276.2Pricing
BP-279674-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneMolecular structure of the compound: 4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione337.1Pricing
BP-279682-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindole-4-carboxylic acidMolecular structure of the compound: 2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindole-4-carboxylic acid302.2Pricing
BP-279692-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindoline-5-carboxylic acidMolecular structure of the compound: 2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindoline-5-carboxylic acid302.2Pricing
BP-24447Thalidomide-AcidMolecular structure of the compound: Thalidomide-Acid332.398%Pricing
BP-279702-(2,6-Dioxopiperidin-3-yl)-5-ethynylisoindoline-1,3-dioneMolecular structure of the compound: 2-(2,6-Dioxopiperidin-3-yl)-5-ethynylisoindoline-1,3-dione282.3Pricing
Thalidomide-O-Acid
BP-28096Thalidomide-O-Hexyl-AcidMolecular structure of the compound: Thalidomide-O-Hexyl-Acid402.4Pricing
Thalidomide-O-PEG-Acid
BP-25490Thalidomide-O-PEG2-AcidMolecular structure of the compound: Thalidomide-O-PEG2-Acid434.498%Pricing
BP-24509Thalidomide-O-PEG4-AcidMolecular structure of the compound: Thalidomide-O-PEG4-Acid522.598%Pricing
BP-25489Thalidomide-O-PEG6-AcidMolecular structure of the compound: Thalidomide-O-PEG6-Acid610.698%Pricing
Thalidomide-O-PEG-Amine
BP-28029Thalidomide-O-PEG2-AmineMolecular structure of the compound: Thalidomide-O-PEG2-Amine405.4Pricing
BP-24435Thalidomide-O-PEG4-AmineMolecular structure of the compound: Thalidomide-O-PEG4-Amine493.598%Pricing
Thalidomide-O-PEG-Azide
BP-24418Thalidomide-O-PEG4-AzideMolecular structure of the compound: Thalidomide-O-PEG4-Azide519.598%Pricing
Thalidomide-O-PEG-Propargyl
BP-24423Thalidomide-O-PEG4-PropargylMolecular structure of the compound: Thalidomide-O-PEG4-Propargyl488.598%Pricing
Thalidomide-O-PEG-NHS ester
BP-25500Thalidomide-O-PEG2-NHS esterMolecular structure of the compound: Thalidomide-O-PEG2-NHS ester531.598%Pricing
BP-24453Thalidomide-O-PEG4-NHS esterMolecular structure of the compound: Thalidomide-O-PEG4-NHS ester619.698%Pricing
BP-25495Thalidomide-O-PEG6-NHS esterMolecular structure of the compound: Thalidomide-O-PEG6-NHS ester707.798%Pricing
Thalidomide-O-PEG-t-butyl ester
BP-24443Thalidomide-O-PEG4-t-butyl esterMolecular structure of the compound: Thalidomide-O-PEG4-t-butyl ester578.698%Pricing
Thalidomide-O-PEG-Tosyl
BP-24478Thalidomide-O-PEG5-TosylMolecular structure of the compound: Thalidomide-O-PEG5-Tosyl648.698%Pricing
Thalidomide-O-acetamido-C4-amine
BP-27849Thalidomide-O-acetamido-C4-amine HCl saltMolecular structure of the compound: Thalidomide-O-acetamido-C4-amine HCl salt402.4Pricing
Thalidomide-O-amido-PEG4-azide
BP-24454Thalidomide-O-amido-PEG4-azideMolecular structure of the compound: Thalidomide-O-amido-PEG4-azide576.698%Pricing
Thalidomide-O-amido-PEG4-propargyl
BP-24456Thalidomide-O-amido-PEG4-propargylMolecular structure of the compound: Thalidomide-O-amido-PEG4-propargyl546.598%Pricing
Thalidomide-5-amine
BP-28030Thalidomide-5-(C6-amine)Molecular structure of the compound: Thalidomide-5-(C6-amine)400.4Pricing
BP-28031Thalidomide-5-(PEG2-amine)Molecular structure of the compound: Thalidomide-5-(PEG2-amine)432.4Pricing
BP-28032Thalidomide-5-(PEG4-amine)Molecular structure of the compound: Thalidomide-5-(PEG4-amine)520.5Pricing
Thalidomide-5-acid
BP-28033Thalidomide-5-(PEG2-acid)Molecular structure of the compound: Thalidomide-5-(PEG2-acid)461.4Pricing
BP-28034Thalidomide-5-(PEG4-acid)Molecular structure of the compound: Thalidomide-5-(PEG4-acid)549.5Pricing
D-Biotin-PEG-Thalidomide
BP-23848D-Biotin-PEG6-ThalidomideMolecular structure of the compound: D-Biotin-PEG6-Thalidomide791.998%Pricing
D-Amino-PEG-Thalidomide
BP-24115D-Amino-PEG6-Thalidomide TFA saltMolecular structure of the compound: D-Amino-PEG6-Thalidomide TFA salt565.698%Pricing
dBET1
BP-27851dBET1Molecular structure of the compound: dBET1785.3Pricing
Pomalidomide
BP-24477PomalidomideMolecular structure of the compound: Pomalidomide273.298%Pricing
Pomalidomide-PEG-Ph-NH2
BP-27848Pomalidomide-PEG4-Ph-NH2Molecular structure of the compound: Pomalidomide-PEG4-Ph-NH2540.6Pricing
Pomalidomide 4'-PEG-azide
BP-27852Pomalidomide 4'-PEG3-azideMolecular structure of the compound: Pomalidomide 4-PEG3-azide474.595%Pricing
Pomalidomide-PEG-Azide
BP-24497Pomalidomide-PEG5-AzideMolecular structure of the compound: Pomalidomide-PEG5-Azide590.698%Pricing
P131
BP-27853P131Molecular structure of the compound: P131913Pricing
ARV-825
BP-27847ARV-825Molecular structure of the compound: ARV-825923.5Pricing
Lenalidomide
BP-27971Phthalimidine, 2-(2,6-dioxopiperiden-3-yl)Molecular structure of the compound: Phthalimidine, 2-(2,6-dioxopiperiden-3-yl)244.3Pricing
BP-27972LenalidomideMolecular structure of the compound: Lenalidomide259.3Pricing
BP-279743-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dioneMolecular structure of the compound: 3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione259.3Pricing
BP-279763-(7-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dioneMolecular structure of the compound: 3-(7-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione259.3Pricing
BP-279753-(6-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dioneMolecular structure of the compound: 3-(6-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione259.3Pricing
BP-279773-(4-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dioneMolecular structure of the compound: 3-(4-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione323.1Pricing
BP-279783-(5-Bromo-1-oxo-2-isoindolinyl)piperidine-2,6-dioneMolecular structure of the compound: 3-(5-Bromo-1-oxo-2-isoindolinyl)piperidine-2,6-dione323.1Pricing
BP-279803-(7-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dioneMolecular structure of the compound: 3-(7-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione323.1Pricing
BP-279793-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dioneMolecular structure of the compound: 3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione323.1Pricing
BP-279813-(5-iodo-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dioneMolecular structure of the compound: 3-(5-iodo-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione370.1Pricing
BP-279822-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acidMolecular structure of the compound: 2-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid288.3Pricing
BP-279832-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindoline-5-carboxylic acidMolecular structure of the compound: 2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindoline-5-carboxylic acid288.3Pricing
Avadomide
BP-279733-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dioneMolecular structure of the compound: 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione286.3Pricing