2-(2,6-Dioxopiperidin-3-yl)-5-hydrazinylisoindoline-1,3-dione, HCl salt is a thalidomide analogue featuring a hydrazine. PROTAC linkers are made to recruit E3 ligase for the ubiquitinylation of target proteins. The hydrazine may be used for further derivatization via reactions with various carbonyl groups.
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