Biotinylation reagents
Biotinylation reagents are very popular labeling reagents in biochemistry and they are commonly used for covalent coupling of biotin to a protein, DNA or other molecules. The non-covalent interaction of the biotin-avidin is very useful for purifying or detecting proteins of interest.BroadPharm provides a wide selection of biotinylation reagents, which can be conjugated with amines, azides, sulfhydryls, carboxyls and carbohydrates. We also provide photoreactive biotin compounds.
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Amine Reactive
Biotin acid, Biotin-NHS esters, Biotin-PEG-NHS esters are amine-reactive biotinylation reagents, PEG spacer in the reagents increase the reagent's water solubility.
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Carbonyl Reactive
Biotin-PEG-Oxyamine and Biotin Hydrazide are aldehyde-reactive biotinylation reagents that contain PEG spacer arms for increased hydrophilicity.
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Carboxyl Reactive
A class of biotin compounds containing a PEG spacer arm and a terminal primary amine for conjugation via EDC and other crosslinker methods. PEGylation increases water solubility to the biotinylated mo...
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Cleavable Biotin
Cleavable biotinylation reagents for selective enrichment of azide, alkyne, NHS active ester, oxyamine, … containing biomolecules.
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Click Chemistry
Azido-, alkyne-, and DBCO containing biotinylation reagents for bioconjugation, biolabeling and chemical modification. Biotin can be subsequently detected with streptavidin, avidin or NeutrAvidin® bio...
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Desthiobiotin
Desthiobiotin is a single-ring, sulfur-free analog of biotin that provides soft-release elution from streptavidin.
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Sulfhydryl Reactive
A class of Biotinylation reagents such as Biotin-PEG-Mal and Biotin-HPDP used to specifically biotinylate antibodies and other biomolecules at sulfhydryl groups.
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Tetrazine Ligation
Methyltetrazine-activated biotinylation reagents react with TCO-containing compounds via a Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond.
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Other Labeling Reagents
Biotinylation regents that contain hydroxyl group, halogen (ie. Iodide).
