Biotinylation reagents are very popular labeling reagents in biochemistry and they are commonly used for covalent coupling of biotin to a protein, DNA or other molecules. The non-covalent interaction of the biotin-avidin is very useful for purifying or detecting proteins of interest. BroadPharm provides a wide selection of biotinylation reagents, which can be conjugated with amines, azides, sulfhydryls, carboxyls and carbohydrates. We also provide photoreactive biotin compounds.
Biotin acid, Biotin-NHS esters, Biotin-PEG-NHS esters are amine-reactive biotinylation reagents, PEG spacer in the reagents increase the reagent's water solubility.
Biotin-PEG-Oxyamine and Biotin Hydrazide are aldehyde-reactive biotinylation reagents that contain PEG spacer arms for increased hydrophilicity.
A class of biotin compounds containing a PEG spacer arm and a terminal primary amine for conjugation via EDC and other crosslinker methods. PEGylation increases water solubility to the biotinylated molecule.
Cleavable biotinylation reagents for selective enrichment of azide, alkyne, NHS active ester, oxyamine, _ containing biomolecules.
Azido-, alkyne-, and DBCO containing biotinylation reagents for bioconjugation, biolabeling and chemical modification. Biotin can be subsequently detected with streptavidin, avidin or NeutrAvidin_ biotin-binding protein.
Desthiobiotin is a single-ring, sulfur-free analog of biotin that provides soft-release elution from streptavidin.
Biotinylation regents that contain hydroxyl group, halogen (ie. Iodide).
A class of Biotinylation reagents such as Biotin-PEG-Mal and Biotin-HPDP used to specifically biotinylate antibodies and other biomolecules at sulfhydryl groups.
Methyltetrazine-activated biotinylation reagents react with TCO-containing compounds via a Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond.