β-Glucuronide Linkers

β-Glucuronide Linkers

β-Glucuronide Linkers is an enzyme-labile linker used in the development of antibody-drug conjugates. The linker is stable in circulation, hydrophilic and provides ADCs that are highly active in vitro and in vivo. Exposure of the drug-linker to β-glucuronidase resulted in facile drug release.

Catalog Product Name Structure M.W. Purity Pricing
β-Glucuronide Linkers
BP-43074MAC glucuronide linker-2Molecular structure of the compound: MAC glucuronide linker-2455.4Pricing
BP-43076Me-triacetyl-ß-D-glucopyranuronate-Ph-CH2OH-FmocMolecular structure of the compound: Me-triacetyl-ß-D-glucopyranuronate-Ph-CH2OH-Fmoc748.7Pricing
BP-43075ß-D-glucuronide-pNP-carbonateMolecular structure of the compound: ß-D-glucuronide-pNP-carbonate913.9Pricing
BP-43175Beta-glucuronide-MMAEMolecular structure of the compound: Beta-glucuronide-MMAE1059.398%Pricing
BP-43664Fmoc-Val-Ala-ß-D-glucuronide-PAB-PNPMolecular structure of the compound: Fmoc-Val-Ala-ß-D-glucuronide-PAB-PNP101398%Pricing
Hydroxymethyl aminophenoxy-sugar
BP-426072-(4-(Hydroxymethyl)-2-aminophenoxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetateMolecular structure of the compound: 2-(4-(Hydroxymethyl)-2-aminophenoxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate455.4Pricing
BP-432332-(4-(Hydroxymethyl)-2-aminophenoxy)-tetra-Ac-beta-D-galactoseMolecular structure of the compound: 2-(4-(Hydroxymethyl)-2-aminophenoxy)-tetra-Ac-beta-D-galactose455.495%Pricing
BP-430172-(4-(Hydroxymethyl)-2-(NH-Fmoc)phenoxy)-6-Beta-D-glucose tetraacetateMolecular structure of the compound: 2-(4-(Hydroxymethyl)-2-(NH-Fmoc)phenoxy)-6-Beta-D-glucose tetraacetate677.795%Pricing
Sophoricoside
BP-42511SophoricosideMolecular structure of the compound: Sophoricoside432.4Pricing
Disogluside
BP-42515DisoglusideMolecular structure of the compound: Disogluside576.8Pricing