β-Glucuronide Linkers

β-Glucuronide Linkers


β-Glucuronide Linkers is an enzyme-labile linker used in the development of antibody-drug conjugates. The linker is stable in circulation, hydrophilic and provides ADCs that are highly active in vitro and in vivo. Exposure of the drug-linker to β-glucuronidase resulted in facile drug release.

Catalog Product Name Structure M.W. Purity Pricing
Glycosidase Cleavable Linker
BP-43074MAC glucuronide linker-2Molecular structure of the compound: MAC glucuronide linker-2455.4Pricing
BP-43076Me-triacetyl-ß-D-glucopyranuronate-Ph-CH2OH-FmocMolecular structure of the compound: Me-triacetyl-ß-D-glucopyranuronate-Ph-CH2OH-Fmoc748.7Pricing
BP-43075ß-D-glucuronide-pNP-carbonateMolecular structure of the compound: ß-D-glucuronide-pNP-carbonate913.9Pricing
BP-43175Beta-glucuronide-MMAEMolecular structure of the compound: Beta-glucuronide-MMAE1059.398%Pricing