PLGA(10k)-PEG(5k)-Thiol is functionalized with thiol group which is reactive with maleimide via thioether linkage formation or with SPDP via disulfide bond formation. The amphiphile polymer contains a hydrophilic PEG block and a hydrophobic poly(lactide-co-glycolide) (PLGA) block. Upon dispersion in water, the polymer can self-assemble to form micelles and can be used to encapsulate hydrophobic drugs. This polymer can be used to prepare drug-loaded nanoparticles for controlled release drug delivery. Reagent grade, for research purpose.
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