Bis-sulfone NHS Ester

Bis-sulfone NHS Ester

Bis-sulfone NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-23344
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    • Price
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    • 100 MG
    • $160.00
    • 500 MG
    • $288.00
    • 1 G
    • $407.00

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Product Citations

  1. Chiang, W., Stout, A., Yanchik-Slade, F., Li, H., Terrando, N., Nilsson, B. L., ... & Krauss, T. D. (2023). Quantum Dot Biomimetic for SARS-CoV-2 to Interrogate Blood–Brain Barrier Damage Relevant to NeuroCOVID Brain Inflammation. ACS Applied Nano Materials, 6(16), 15094-15107.