Folate-PEG-amine, MW 1,000 can bind to folate receptors on the surface of a broad spectrum of cancer tissue. The polymer can be used to design nanoparticles-based therapy via folate receptor which minimizes nonspecific uptake in normal cells. The terminal amine can react with a variety of functional groups, such as succinimidyl ester (NHS) or carboxylic acid (COOH) in the presence of HATU or EDC. The 1k PEG polymer improves the water solubility of the compound. Reagent grade, for research purpose.
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