Alkyne-Val-Cit-PAB-FAM

Alkyne-Val-Cit-PAB-FAM


FAM-amido hexamethylene carbamate-PAB-Cit-Val-Alkyne is a cleavable ADC linker with fluorescein that undergoes enzymatic transamination. The alkyne group can react with azides via copper catalyzed Click Chemistry reactions. The Val-Cit linker was designed to be cleaved by cathepsin B. Since this enzyme is only present in the lysosome, the ADC payload will be released only in the cell.

Molecular structure of the compound BP-26355
    • Unit
    • Price
    • Qty
    • 10 MG
    • $540.00
    • 25 MG
    • $980.00

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