Alkyne-pGlu, MW 20,000 is a chemical reagent containing a terminal alkyne ligated to a poly(glutamic acid) peptide. The terminal alkyne is commonly used in copper (I) click chemistry to form stable triazoles with azides. Poly(glutamic acid) is a peptide polymer which is commonly used in cosmetics and drug delivery. The carboxylic acid in each amino acid monomer is capable of reacting with nucleophiles such as amines or thiols to form stable, water soluble bonds.
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