DBCO-PEG2-Val-Cit-PAB-Exatecan is a cleavable ADC linker. It includs a Cathepsin-cleavable Val-Cit dipeptide, PAB moeity, exatecan payload, and DBCO group; A click chemistry handle that readily reacts with azide groups. The PEG2 chain increases the hydrophilicity of the compound.
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