t-butyl ester-PEG-succinimidyl carbonate, MW 5,000 constitutes a polyPEG reagent containing a succinimidyl carbonate group, which is a good leaving group and commonly reacts with amine nucleophiles. The t-butyl group can be deprotected under acidic conditions. The 5k PEG polymer greatly enhances the water-solubility of the molecule.
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