PC Mal-PEG3-biotin functions as a photocleavable biotinylated reagent containing biotin, which has a strong binding with avidin or streptavidin for protein labeling or purification, and maleimide group, which will react with a thiol group. The PEG spacer imparts solubility in aqueous media. This structure allows for efficient photorelease of linked molecules, typically achieving over 90% cleavage in 5-25 minutes using a near-UV lamp.
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