BP Lipid 449 is a novel analog of the ionizable lipid LP01 whose key feature is the introduction of a bis cyclopropyl fatty acid tail. This alteration has been designed to investigate the effect on the dynamics of lipid nanoparticles as cyclopropane fatty acids have been reported to affect the fluidity and structure of lipid bilayers in response changes in temperature and pH (J. Phys. Chem. B 2014, 118, 48, 13838–13848). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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