LC-MB12 is an orally active PROTAC designed for the degradation of FGFR2. This compound integrates a FGFR2 inhibitor, a PROTAC linker, and a cereblon-binding moiety, effectively disrupting FGFR2 signaling in gastric cancer cells. Its structural components facilitate targeted protein degradation, highlighting its potential in research focused on tumor biology.
Usually ships within 24 hours.