PROTAC IDO1 Degrader-1 is a bifunctional molecule designed to target indoleamine 2,3-dioxygenase 1 (IDO1) for degradation by recruiting it to the Cereblon E3 ligase, leading to its ubiquitination and subsequent breakdown via the ubiquitin-proteasome system. It has been shown to enhance the activity of certain immune cells in a research context.
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