Fmoc-Gly-Gly-Gly-PEG8-acid represents a cleavable tripeptide PEG linker applied in the synthesis of antibody-drug conjugates (ADCs). The acid moiety can be used in peptide coupling with amines via activators. The Fmoc group can be deprotected under basic conditions to obtain the free amine. The PEG8 chain improves the hydrophilicity of the molecule.
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