TAMRA-PEG4-Tetrazine is a tatrazine attached tetramethylrhodamine (TAMRA) dye. Rhodamine is a commonly used red fluorescent dye tracer in biology for staining cells, tissues, biomarkers or nanoparticles. It has peak fluorescence emission at 572-575 nm. Tetrazin demonstrates exceptionally fast cycloaddition kinetics (up to 30 000 M-1 s-1) with trans-cyclooctene (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction.
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