4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide

4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide


APN-amine is a heterobifunctional linker containing an APN moiety with exquisite chemoselectivity for cysteine and an amine group. The superior stability of APN-cysteine conjugates in aqueous media, human plasma, and living cells makes this new thiol-click reaction a promising methodology for applications in bioconjugation.

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