Lipid is a class of organic compounds that are fatty acids or their derivatives that are insoluble in water but soluble in organic solvents. They include many natural oils, waxes, and steroids or their derivatives. The functions of lipids include storing energy, signaling, and acting as structural components of cell membranes. Lipids have become widely used in the cosmetic and food industries as well as in nanoparticle drug technology. The amphiphilic nature of some lipids allows them to form structures such as vesicles, multilamellar/unilamellar liposomes, or membranes in an aqueous environment. There are four main kinds of lipids used in lipid nanoparticle (LNP) drug delivery vehicle. Cationic Lipid, Ionizable Lipid, PEG lipid, Helper Lipid.