Fmoc-N-amido-PEG2-acid

Fmoc-N-amido-PEG2-acid

Fmoc-N-amido-PEG2-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-21627
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    • 1 G
    • $110.00
    • 5 G
    • $240.00
    • 10 G
    • $370.00

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Product Citations

  1. Tong, Y., Gu, M., Luo, X., Qi, H., Jiang, W., Deng, Y., ... & Hu, Y. (2023). An engineered nanoplatform cascade to relieve extracellular acidity and enhance resistance-free chemotherapy. Journal of Controlled Release, 363, 562-573.
    https://www.sciencedirect.com/science/article/abs/pii/S0168365923006557
  2. Upadhya, Rahul, Matthew Tamasi, Elena Di Mare, Sanjeeva Murthy, and Adam Gormley Data-Driven Design of Protein-Like Single-Chain Polymer Nanoparticles. ChemRxiv. 2022
    https://chemrxiv.org/engage/chemrxiv/article-details/631f37eabe03b23be6f3014d