Tetrazine-NHS ester

Tetrazine-NHS ester


Tetrazine-NHS Ester is a NHS activated tetrazine linker. NHS ester is very reactive with amine containing molecule. Tetrazine enable fast click reaction with TCO (trans-cycloctene). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-22946
    • Unit
    • Price
    • Qty
    • 50 MG
    • $275.00
    • 100 MG
    • $407.00
    • 500 MG
    • $1185.00
    • 1 G
    • $1741.00

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Product Citations


  1. Alshehri, S., Rawat, P., Basiri, A., Zhang, W., Fan, W., Rikhtechi, P., & Garrison, J. C. (2023). Exploration of a Pretargeted Theranostic Copolymer Employing Inverse Electron-Demand Diels–Alder Conjugation in Ovarian Cancer. ACS Applied Polymer Materials, 6(1), 218-231.
    https://pubs.acs.org/doi/abs/10.1021/acsapm.3c01849
  2. Otaru, Sofia, Andreas Paulus, Surachet Imlimthan, Iida Kuurne, Helena Virtanen, Heidi Liljenba?ck, Tuula Tolvanen et al. Development of [18F] AmBF3 Tetrazine for Radiolabeling of Peptides: Preclinical Evaluation and PET Imaging of [18F] AmBF3-PEG7-Tyr3-Octreotide in an AR42J Pancreatic Carcinoma Model.. Bioconjugate Chemistry 33, no. 7 (2022): 1393-1404.. 2022
    https://pubs.acs.org/doi/full/10.1021/acs.bioconjchem.2c00231
  3. Otaru, Sofia, Tatu Martinmäki, Iida Kuurne, Andreas Paulus, Kerttuli Helariutta, Mirkka Sarparanta, and Anu J. Airaksinen Radiolabelling of peptides with tetrazine ligation based on the inverse electron-demand Diels–Alder reaction: rapid, catalyst-free and mild conversion of 1, 4-dihydropyridazines to pyridazines.  RSC advances. 2023
    https://pubs.rsc.org/en/content/articlehtml/2023/ra/d3ra02807k