DOTAP

DOTAP

DOTAP, 1,2-Dioleoyl-3-trimethylammonium propane is a di-chain, or gemini, cationic surfactant. DOTAP has been used for in vitro and in vivo nucleic acid and protein delivery.

Molecular structure of the compound BP-25622
    • Unit
    • Price
    • Qty
    • 100 MG
    • $260.00
    • 250 MG
    • $450.00
    • 500 MG
    • $650.00
    • 1 G
    • $980.00

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Product Citations

  1. Espy, C. L.; Wu, J.; Omo‐Lamai, S.; Wang, L.; Dong, F.; Milosavljevic, A.; O’Neill, S.; Brysgel, T.; Wang, Y.; Zaleski, M.; Wolfe, E.; Maheshwari, R.; Patel, M.; Trauner, D.; Nong, J.; Wang, Z.; Brenner, J. S. Localized NF‐ΚB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation. Advanced Science 2026.
    https://doi.org/10.1002/advs.202517931
  2. Kim, B., Seo, H. W., Lee, K., Yong, D., Park, Y. K., Lee, Y., ... & Ryu, C. M. (2024). Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection. Advanced Healthcare Materials, 2403281.
    https://doi.org/10.1002/adhm.202403281
  3. Ko, K. H., Lee, S. H., Choi, Y. H., Kang, S. M., Yang, H. S., Lee, S. M., ... & Cha, S. B. (2025). Lipid nanoparticle encapsulated TLR3 agonist adjuvant elicits potent T cell immunity against cancer and viruses. npj Vaccines.
    https://www.nature.com/articles/s41541-025-01349-w