DBCO-PEG24-NHS ester

DBCO-PEG24-NHS ester


DBCO-PEG24-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-25726
    • Unit
    • Price
    • Qty
    • 10 MG
    • $210.00
    • 25 MG
    • $430.00
    • 50 MG
    • $720.00
    • 100 MG
    • $1140.00

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Product Citations


  1. Luo, D., Wang, N., Major-Monfried, H., Ralls, J., Rha, S., Maitland, S. A., ... & Kentsis, A. (2025). Modular platform for therapeutic drug delivery using trifunctional bio-orthogonal macromolecular conjugates. bioRxiv, 2025-07.
    https://www.biorxiv.org/content/10.1101/2025.07.24.666613v1.full