Desthiobiotin-PEG3-Azide
Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd?= 1011?vs. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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Catalog:
BP-22473
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Name:
Desthiobiotin-PEG3-Azide
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Formula:
C18H34N6O5
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MW:
414.5
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CAS:
1426828-06-9
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Purity:
98%
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Ships Within:
24 Hours
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Storage Condition:
-20°C
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Shipping:
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Availability:
In Stock
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NMR:
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SDS:
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