Boc-PEG6-Val-Cit-PAB-OH
Boc-PEG6-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker intermediate featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The PAB group features a free benzylic alcohol which may be used to link to a drug payload. The Boc protecting group may be removed with acid to release a primary amine which can be used for further conjugation. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
-
Catalog:
BP-23217
-
Name:
Boc-PEG6-Val-Cit-PAB-OH
-
Formula:
C38H66N6O13
-
MW:
815
-
CAS:
2055024-53-6
-
Purity:
-
Ships Within:
24 Hours
-
Storage Condition:
-20°C
-
Shipping:
Ambient Temperature
-
NMR:
View
-
SDS:
View