Boc-PEG6-Val-Cit-PAB-OH

Boc-PEG6-Val-Cit-PAB-OH


Boc-PEG6-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker intermediate featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The PAB group features a free benzylic alcohol which may be used to link to a drug payload. The Boc protecting group may be removed with acid to release a primary amine which can be used for further conjugation. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.

Molecular structure of the compound BP-23217
    • Unit
    • Price
    • Qty
    • 50 MG
    • $380.00
    • 100 MG
    • $650.00
    • 250 MG
    • $980.00
    • 500 MG
    • $1500.00

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