Azido-PEG3-Val-Cit-PAB-PNP

Azido-PEG3-Val-Cit-PAB-PNP

Azido-PEG3-Val-Cit-PAB-PNP is a cleavable peptide ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. PNP groupg is a good leaving group when treating with aminebearing payload. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility. . Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-23368
    • Unit
    • Price
    • Qty
    • 50 MG
    • $750.00
    • 100 MG
    • $1200.00
    • 250 MG
    • $2300.00

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Product Citations

  1. Gonzalez, Paulina, Sashi Debnath, Yu-An Chen, Elizabeth Hernandez, Preeti Jha, Marianna Dakanali, Jer-Tsong Hsieh, and Xiankai Sun. A Theranostic Small-Molecule Prodrug Conjugate for Neuroendocrine Prostate Cancer. Pharaceutics. 2023
    https://www.mdpi.com/1999-4923/15/2/481?trk=organization_guest_main-feed-card-text