PFI 1

PFI 1


PFI 1 is a BET bromodomain inhibitor that exhibits inhibitory activity at BRD2 and BRD4. PFI-1 is a selective BET bromodomain inhibitor with activity at BRD2 (IC50 = 98 nM) and BRD4 (IC50 = 220 nM). PFI 1 induces apoptosis and G1 cell cycle arrest in BET inhibitor-sensitive cell lines (MV4;11). PFI 1 also downregulates Aurora B expression in MV4;11 cells. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-25371
    • Unit
    • Price
    • Qty
    • 10 MG
    • $130.00
    • 25 MG
    • $280.00
    • 50 MG
    • $420.00

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