Azide-Polysarcosine100

Azide-Polysarcosine100


Azide-Polysarcosine100 is a lipid-polypeptoid conjugate based on the endogenous amino acid sarcosine (N-methylated glycine) with an average of 100 sarcosine units. The azide (N3) group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Polysarcosine has been shown to have a higher protein secretion with a reduced immunostimulatory response observed when compared to systems based on polyethylene glycol (PEG) lipids. Azide-Polysarcosine can be used to create lipids for the formation of lipid nanoparticles (LNPs) to be used in therapeutic applications of mRNA.

Molecular structure of the compound BP-28439
    • Unit
    • Price
    • Qty
    • 50 MG
    • $480.00
    • 100 MG
    • $860.00
    • 250 MG
    • $1300.00

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