Azido-PEG1-Val-Cit-PAB-PNP

Azido-PEG1-Val-Cit-PAB-PNP


Azido-PEG1-Val-Cit-PAB-PNP constitutes a cleavable ADC linker used in antibody-drug conjugates (ADCs). The Val-Cit linker was designed to be cleaved by cathepsin B. The PNP group is a good leaving group when reacting with amine-bearing payloads. Additionally, the azido group reacts with DBCO, BCN, or linear alkyne groups via click chemistry. The PEG unit enhances the water-solubility of the molecule.

Molecular structure of the compound BP-41933
    • Unit
    • Price
    • Qty
    • 50 MG
    • $750.00
    • 100 MG
    • $1200.00
    • 250 MG
    • $2300.00

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