Azido-PEG4-Val-Ala-PAB-SN38 serves as a cleavable ADC linker featuring a cleavable Val-Cit dipeptide, a PAB group, and an SN38 warhead. The PEG linker improves the solubility of the compound. The azide moiety can perform click chemistry reactions with BCN, DBCO, and linear alkynes.
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