N-dodecanoyl-L-homoserine lactone

N-dodecanoyl-L-homoserine lactone

N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-κB in RAW 264.7 macrophages, increasing the expression of TNF-α, interleukin-1β (IL-1β), and IL-8, while other lactones do not.4 In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte (HaCaT) cells.

Molecular structure of the compound BP-43084
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    • Price
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    • 50 MG
    • $230.00
    • 100 MG
    • $420.00
    • 250 MG
    • $750.00
    • 500 MG
    • $1120.00

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