Acid-PEG8-GGFG-DXD is a cleavable ADC linker-payload compound for the creation of antibody-drug conjugates (ADCs). The carboxylic group is reactive with primary amines via activators such as HATU. DXD, a derivative of Exatecan, is a DNA topoisomerase I inhibitor as an ADC payload. The PEG8 units boosts the solubility of the conjugate in aqueous media.
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