N-(Azido-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) is a advanced dual payload linker molecule which attached both MMAE and Exatecan. This unique payload-linker allows one antibody to conjugate with two different payloads in one-step, which can target cancers through different mechanisms, increase drug potency, and decrease drug resistance. The branched structure allows for more attachment of ADC payloads.
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