N-(Mal)-N-(PEG8-Val-Cit-PAB-MMAE)-N-(PEG8-Val-Cit-PAB-Exatecan)

N-(Mal)-N-(PEG8-Val-Cit-PAB-MMAE)-N-(PEG8-Val-Cit-PAB-Exatecan)


N-(Mal)-N-(PEG8-Val-Cit-PAB-MMAE)-N-(PEG8-Val-Cit-PAB-Exatecan) is an advanced dual-payload linker that carries both MMAE and Exatecan. This unique design with the maleimide moiety enables the conjugation with antibody in one step. The two distinct therapeutic payloads are linked to the same antibody, delivering synergistic effects that maximize treatment efficacy while reducing the risk of drug resistance.

Molecular structure of the compound BP-44255

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