Mal-Val-Cit-BP Fluor 488 is a fluorescent dye linked to a cleavable linker, which may be employed in ADC research and development. The BP Fluor 488 is a pure 5-sulfonated rhodamine molecule, and it eliminates the lot-to-lot variation caused by isomer ratio differences. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The Val-Cit dipeptide is cathepsin-cleavable, and the maleimide can conjugate with cysteine-bearing biomolecules (e.g., antibody).
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