Brentuximab vedotin

Brentuximab vedotin (ADCETRIS) is a CD30-directed antibody-drug conjugate (ADC) consisting of three components: 1) the chimeric IgG1 antibody cAC10, specific for human CD30, 2) the microtubule disrupting agent MMAE, and 3) a protease-cleavable linker that covalently attaches MMAE to cAC10. Brentuximab vedotin has an approximate molecular weight of 153 kDa. Approximately 4 molecules of MMAE are attached to each antibody molecule.This product is for research use only.

Product Details
Species Reactivity	Human
Type	Antibody-drug conjugate
ADC antibody	Brentuximab (Anti-CD30)
ADC cytotoxin (drug)	MMAE
Immunogen	Human CD30
DAR (Drug to Antibody Ratio)	~4.2
Purity	99%
Molecular Weight	153kDa
Storage Condition	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
Storage Buffer	1x PBS