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Azintuxizumab vedotin
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Azintuxizumab vedotin
Azintuxizumab vedotin
Catalog #: bp-50217
Catalog #
Unit
Price
Qty
BP-50217
1 mg
$950.00
BP-50217
5 mg
$2800.00
Usually ships within 24 hours.
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Overview
Azintuxizumab vedotin (ABBV-838) is an antibody–drug conjugate (ADC) targeting a unique epitope of CD2 subset 1, a cell-surface glycoprotein expressed on multiple myeloma cells. Azintuxizumab vedotin is composed of an anti-CD2, IgG1κ, antibody, an enzymatically cleavable peptide-linker, the cytotoxic agent Monomethyl auristatin E (MMAE). Sofituzumab Vedotin has a Drug-to-antibody ratio (DAR) of 4, it shows single-agent antitumor activity in mouse models using human myeloma xenografts. This product is for research use only.
Product Details
Species Reactivity
Human
Type
Antibody-drug conjugate
ADC antibody
Azintuxizumab (anti-CD2)
ADC cytotoxin (drug)
MMAE
Immunogen
Human CD2
DAR (Drug to Antibody Ratio)
~ 4.0
Purity
98%
Molecular Weight
N/A
Storage Condition
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
Storage Buffer
1xPBS
Images
Datasheets and Documents
Datasheet BP-50217.pdf
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