2'-Deoxyuridine is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. 2'-Deoxyuridine has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-Deoxyuridine has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate. 2'-Deoxyuridine is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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