TCO-PEG

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The tetrazine ligation is the reaction of a trans-cyclooctene and an s-tetrazine in an inverse electron demand Diels Alder (IEDDA) reaction followed by a retro-Diels Alder reaction to eliminate nitrogen gas. This is a fast reaction with a second order rate constant of 2000 M−1–s−1 (in 9:1 methanol/water) allowing modification of biomolecules at very low concentrations. This ligation can be performed in aqueous media with very fast speed. Reactions have also been performed using TCO or norbornenes as dienophiles at second order rates on the order of 1 M−1•s−1 in aqueous media. The reaction has been applied in labeling live cells and other bio-entities.

TCO-PEG
Catalog No. Name Structure M.W. Purity Pricing

TCO-PEG-Acid

BP-24153 TCO-PEG2-acid TCO-PEG2-acid 329.4 Pricing
BP-24143 TCO-PEG3-acid TCO-PEG3-acid 373.5 98% Pricing
BP-22420 TCO-PEG4-acid TCO-PEG4-acid 417.5 98% Pricing
BP-24155 TCO-PEG6-acid TCO-PEG6-acid 505.6 Pricing
BP-24133 TCO-PEG8-acid TCO-PEG8-acid 593.7 98% Pricing
BP-24072 TCO-PEG12-acid TCO-PEG12-acid 769.9 98% Pricing
BP-24087 TCO-PEG24-acid TCO-PEG24-acid 1298.6 98% Pricing
BP-24068 TCO-PEG36-acid TCO-PEG36-acid 1827.2 98% Pricing

TCO-PEG-NHS ester

BP-22417 TCO-NHS ester TCO-NHS ester 267.3 98% Pricing
BP-24154 TCO-PEG2-NHS ester TCO-PEG2-NHS ester 426.5 Pricing
BP-24147 TCO-PEG3-NHS ester TCO-PEG3-NHS ester 470.5 98% Pricing
BP-22418 TCO-PEG4-NHS ester TCO-PEG4-NHS ester 514.6 95% Pricing
BP-24156 TCO-PEG6-NHS ester TCO-PEG6-NHS ester 602.7 Pricing
BP-24157 TCO-PEG8-NHS ester TCO-PEG8-NHS ester 690.8 Pricing
BP-24123 TCO-PEG12-NHS ester TCO-PEG12-NHS ester 867.0 Pricing
BP-23970 TCO-PEG24-NHS ester TCO-PEG24-NHS ester 1395.6 98% Pricing

TCO-PEG-TFP ester

BP-24129 TCO-PEG8-TFP ester TCO-PEG8-TFP ester 741.8 98% Pricing
BP-24128 TCO-PEG12-TFP ester TCO-PEG12-TFP ester 918.0 98% Pricing

TCO-PEG-PNB

BP-22943 TCO-PNB Ester TCO-PNB Ester 291.3 98% Pricing

TCO-PEG-Amine

BP-22422 TCO-amine hydrochloride TCO-amine hydrochloride 226.3 98% Pricing
BP-24158 TCO-PEG2-amine TCO-PEG2-amine 300.4 Pricing
BP-24099 TCO-PEG3-amine TCO-PEG3-amine 344.5 98% Pricing
BP-24101 TCO-PEG4-amine TCO-PEG4-amine 388.5 Pricing
BP-24159 TCO-PEG6-amine TCO-PEG6-amine 476.6 Pricing
BP-24162 TCO-PEG8-amine TCO-PEG8-amine 564.7 Pricing
 
BP-23320 TCO-C3-PEG3-C3-amine TCO-C3-PEG3-C3-amine 372.5 98% Pricing

TCO-PEG-biotin

BP-23847 TCO-PEG4-biotin TCO-PEG4-biotin 614.8 98% Pricing

TCO-PEG-DBCO

BP-24160 TCO-PEG4-DBCO TCO-PEG4-DBCO 675.8 Pricing
BP-22423 TCO-PEG12-DBCO TCO-PEG12-DBCO 1028.3 95% Pricing

TCO-PEG-Maleimide

BP-23872 TCO-PEG9-maleimide TCO-PEG9-maleimide 759.9 98% Pricing

TCO-PEG-triethoxysilane

BP-24140 TCO-PEG3-triethoxysilane TCO-PEG3-triethoxysilane 576.8 98% Pricing

TCO-PEG-OH

BP-23975 TCO-OH TCO-OH 126.2 98% Pricing

TCO-PEG-TCO

BP-25000 TCO-PEG3-TCO TCO-PEG3-TCO 496.6 95% Pricing
BP-24100 TCO-PEG4-TCO TCO-PEG4-TCO 540.7 96% Pricing
BP-24102 TCO-PEG-TCO, MW5K TCO-PEG-TCO, MW5K Pricing