TCO-PEG

TCO-PEG


TCO PEG linkers (reagents) are a class of PEG linkers with PEG attached to a TCO group (trans-cycloctene), TCO reagent is highly reactive with tetrazine in an inverse electron demand Diels Alder (IEDDA) reaction followed by a retro-Diels Alder reaction to eliminate nitrogen gas. This is a fast reaction with a second order rate constant of 2000 M 1 s 1 (in 9:1 methanol/water) allowing modification of biomolecules at very low concentrations. Reactions have also been performed using TCO or norbornenes as dienophiles at second order rates on the order of 1 M 1 s 1 in aqueous media. This reaction has been applied in labeling live cells, molecular imaging and other bioconjugation applications.

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Catalog Product Name Structure M.W. Purity Pricing
TCO-PEG-Acid
BP-24143TCO-PEG3-acid373.595%Pricing
BP-22420TCO-PEG4-acid417.595%Pricing
BP-24155TCO-PEG6-acid505.695%Pricing
BP-24133TCO-PEG8-acid593.795%Pricing
BP-24072TCO-PEG12-acid769.995%Pricing
BP-24087TCO-PEG24-acid1298.695%Pricing
BP-24068TCO-PEG36-acid1827.295%Pricing
TCO-PEG-NHS ester
BP-22417TCO-NHS ester267.395%Pricing
BP-24147TCO-PEG3-NHS ester470.595%Pricing
BP-22418TCO-PEG4-NHS ester514.695%Pricing
BP-24156TCO-PEG6-NHS ester602.795%Pricing
BP-24157TCO-PEG8-NHS ester690.895%Pricing
BP-24123TCO-PEG12-NHS ester867.095%Pricing
BP-23970TCO-PEG24-NHS ester1395.695%Pricing
BP-25127TCO-PEG36-NHS ester1924.395%Pricing
BP-24330TCO-PEG2-Sulfo-NHS ester679.895%Pricing
TCO-PEG-TFP ester
BP-24129TCO-PEG8-TFP ester741.895%Pricing
BP-24128TCO-PEG12-TFP ester918.095%Pricing
TCO-PEG-PNB
BP-22943TCO-PNB Ester291.395%Pricing
TCO-PEG-Amine
BP-22422TCO-amine hydrochloride226.395%Pricing
BP-24158TCO-PEG2-amine300.495%Pricing
BP-24099TCO-PEG3-amine344.595%Pricing
BP-24101TCO-PEG4-amine388.595%Pricing
BP-24159TCO-PEG6-amine476.695%Pricing
BP-24162TCO-PEG8-amine564.795%Pricing
BP-23320TCO-C3-PEG3-C3-amine372.595%Pricing
TCO-PEG-biotin
BP-23847TCO-PEG4-biotin614.895%Pricing
TCO-PEG-DBCO
BP-24160TCO-PEG4-DBCO675.895%Pricing
BP-22423TCO-PEG12-DBCO1028.395%Pricing
TCO-PEG-Maleimide
BP-23872TCO-PEG9-maleimide759.995%Pricing
TCO-PEG-triethoxysilane
BP-24140TCO-PEG3-triethoxysilane576.895%Pricing
TCO-PEG-OH
BP-23975TCO-OH126.295%Pricing
BP-24482TCO-PEG3-alcohol301.495%Pricing
TCO-PEG-TCO
BP-24444TCO-PEG2-TCO452.695%Pricing
BP-25000TCO-PEG3-TCO496.695%Pricing
BP-24100TCO-PEG4-TCO540.795%Pricing
BP-24259TCO-PEG8-TCO716.995%Pricing
BP-24102TCO-PEG-TCO, MW5KPricing
TCO-PEG-peptide
BP-24190Gly-Gly-Gly-PEG3-TCO515.695%Pricing
BP-24462TCO-PEG4-Fmoc-Gly-Gly-Gly781.995%Pricing